Tools for Exploration

Working in the lab

The Institute operates the following facilities and equipment for chemical and biological research:

Tissue Culture Laboratory: The institute maintains many cell lines including several dozen human and animal tumor cell lines. This laboratory is extensively equipped and includes centrifugation, fluorescence microscopy and quantitative PCR (qPCR) instrumentation.
The institute operates many high performance liquid chromatography (HPLC) systems for the analysis and purification of small molecules, proteins, etc., as well as gel permeation chromatography. These instruments are equipped with UV-vis, refractive index, fluorescence, conductivity and evaporative light scattering detectors.
Inert Atmosphere Glove Boxes: The institute operates five Vacuum Atmospheres inert atmosphere glove boxes, including the first commercially produced prototype glove box built by D. L Herring in his garage. Our group is still using this system after more than four decades!
Spectroscopy: The I2NM2 operates many spectroscopic instruments, including several single and dual-beam UV-vis, FTIR, fluorescence and chemiluminescence, refractive index and multi-wavelength polarimeters.

High-throughput Tissue Analysis Laboratory: The institute houses a tissue composition analysis laboratory equipped with a high-throughput microwave digestion system and an automated inductively coupled plasma atomic emission spectrometer (ICP-AES). Over the past two years, this laboratory has analyzed more than 10,000 tissue samples and supports several of the institute’s research initiatives, including BNCT and MRI contrast agent development.

Autoclave Reaction Laboratory: The institute houses a high pressure autoclave reaction laboratory equipped for reactions between less than 1 ml, to over one liter in volume. This laboratory is also equipped with two robotic microwave reaction systems for running many automated reactions in series using volumes between 200 ul and 20 ml, operating under pressures of up to 300 PSI and temperatures up to 250 degrees Celsius.

Laser Particle Scattering: The institute operates two instruments capable of determining hydrodynamic particle size between 0.6 nanometers and 10 microns. Measurements of zetapotential are also possible with these instruments.